Área 7. Biotecnología. Aplicaciones Sanitarias de Biociencias
OBJETIVOS CIENTÍFICOS VINCULADOS AL PLAN ESTRATÉGICO
- Generar conocimiento científico de excelencia: se refleja una caída importante con respecto a años anteriores en el número de artículos publicados. Los indicadores cualitativos se mantienen pero se ha perdido bastante liderazgo científico.
- Captación de talento científico: Se ha conseguido un nuevo recurso humano competitivo. El número de investigadores también ha aumentado considerablemente gracias a la financiación competitiva y no competitiva de los grupos. El área ha crecido también con la llegada de un grupo clínico asociado.
- Dinamizar la captación de recursos: la captación de recursos ha mejorado notablemente alcanzando los 1.4 millones de euros en ayudas competitivas concedidas mejorando las capacidades de captación de recursos en convocatorias del plan nacional y manteniendo la financiación europea. Sin embargo, en 2022 no se han ingresado nuevos fondos por investigación en ensayos clínicos.
- Personal
- Publicaciones
- Listado Publicaciones
- Ayudas de Investigación
- Investigación Clínica
- Tesis Doctorales
11
Grupos de Investigación
- BIOLOGÍA DE LA REPRODUCCIÓN (CONSOLIDADO)
- BIOMEMBRANAS Y SEÑALIZACIÓN CELULAR (CONSOLIDADO)
- BIOQUIMICA Y BIOTECNOLOGIA ENZIMATICA (CONSOLIDADO)
- FISIOLOGÍA REPRODUCTIVA Y REPRODUCCIÓN ASISTIDA (CONSOLIDADO)
- BIOLOGÍA MOLECULAR DE SISTEMAS (CONSOLIDADO)
- INVESTIGACIÓN EN GINECOLOGÍA, REPRODUCCIÓN Y MEDICINA MATERNO-FETAL (CONSOLIDADO)
- TECNOLOGÍAS DE MODELADO, PROCESAMIENTO Y GESTIÓN DEL CONOCIMIENTO (CONSOLIDADO)
- GRUPO DE INVESTIGACIÓN EN RADIOLOGÍA (EMERGENTE)
- GRUPO DE RADIOFARMACIA (CLÍNICO ASOCIADO)
- GRUPO DE INVESTIGACIÓN EN FÍSICA MÉDICA (EMERGENTE)
- FARMACOCINETICA CLINICA Y FARMACOTERAPIA APLICADA (CLÍNICO ASOCIADO)
INDICADORES GENERALES
48
Nº Publicaciones
231.24
Impacto Total
4.82
Impacto Medio
| Tipo | Nº Pubs | FI total | FI Medio |
| Originales | 45 (93.75%) | 216.34 | 4.81 |
| Revisiones | 3 (6.25%) | 14.9 | 4.97 |
75.0
Q1%
18.75
D1%
0
FI >= 15
| Tipo | Nº Q1 | Nº D1 | Nº FI >= 15 |
| Originales | 34 | 8 | 0 |
| Revisiones | 2 | 1 | 0 |
INDICADORES DE LIDERAZGO
19
(40.0%)
Nº Publicaciones
101.39
Impacto Total
5.34
Impacto Medio
| Nº Pubs | FI total | FI Medio | |
| Mujer | 9 (47.37%) | 46.06 | 5.12 |
| Hombre | 10 (52.63%) | 55.33 | 5.53 |
73.68
Q1%
26.32
D1%
0
FI >= 15
| Nº Q1 | Nº D1 | Nº FI >= 15 | |
| Mujer | 6 | 3 | 0 |
| Hombre | 8 | 2 | 0 |
OTROS INDICADORES
18.48
HCP10% (2018-2022)
63.93
HCP10 Liderado% (2018-2022)
34.43
HCP10 Lid. Mujeres% (2018-2022)
1.18
Crown (2018-2022)
72.92
Open Access%
52.08
Col. International%
* Se muestran las 5 especies, los 10 genes y las 20 enfermedades más nombradas. Los valores están normalizados logarítmicamente en base al número de publicaciones.
INDICADORES EVOLUTIVOS
DESTACADAS
Cuenca-Guardiola J, de la Morena-Barrio B*, Garcia JL, ..., Fernandez-Breis JT*.
Improvement of large copy number variant detection by whole genome nanopore sequencing.
Journal of Advanced Research, 2022, S2090-1232(22)00241-7 [pii], PMID: 36323370, FI: 10.7
Navarro-Orcajada S, Conesa I, Vidal-Sanchez FJ, ..., Lopez-Nicolas JM*.
Stilbenes: Characterization, bioactivity, encapsulation and structural modifications. A review of their current limitations and promising approaches.
Critical Reviews in Food Science and Nutrition, 2022, , 1-19, PMID: 35234546, FI: 10.2
Henarejos-Escudero P, Hernandez-Garcia S, Martinez-Rodriguez P, ..., Gandia-Herrero F*.
Bioactive potential and spectroscopical characterization of a novel family of plant pigments betalains derived from dopamine.
Food Research International, 2022, 162, 111956, PMID: 36461207, FI: 8.1
Ortega-Forte E*, Hernandez-Garcia S, Vigueras G, ..., Ruiz J*, Gandia-Herrero F*.
Potent anticancer activity of a novel iridium metallodrug via oncosis.
Cellular and Molecular Life Sciences, 2022, 79, 510, PMID: 36066676, FI: 8.0
Castell-Diaz J, Abad-Navarro F, de la Morena-Barrio ME, ..., Fernandez-Breis JT*.
Using Machine Learning for Predicting the Effect of Mutations in the Initiation Codon.
Ieee Journal of Biomedical and Health Informatics, 2022, 26, 5750-5756, PMID: 35998169, FI: 7.7
LISTADO COMPLETO
Moreno-Fernandez J, Ochoa JJ, De Paco Matallana C et al.
COVID-19 during Gestation: Maternal Implications of Evoked Oxidative Stress and Iron Metabolism Impairment.
, 2022, 11, PMID: 35204067, FI: 7.675
Martinez CA, Cuello C, Parrilla I, ..., Martinez EA.
Exogenous Melatonin in the Culture Medium Does Not Affect the Development of In Vivo-Derived Pig Embryos but Substantially Improves the Quality of In Vitro-Produced Embryos.
, 2022, 11, PMID: 35740074, FI: 7.675
Alcaraz M, Olivares A, Andreu-Galvez M, ..., Alcaraz-Saura M.
Paradoxical Radiosensitizing Effect of Carnosic Acid on B16F10 Metastatic Melanoma Cells: A New Treatment Strategy.
, 2022, 11, PMID: 36358539, FI: 7.675
Gil MM, Rodriguez-Fernandez M, Elger T, ..., De Paco Matallana C et al.
Risk of fetal loss after chorionic villus sampling in twin pregnancy derived from propensity score matching analysis.
Ultrasound in Obstetrics & Gynecology, 2022, 59, 162-168, PMID: 34845786, FI: 7.1
Henarejos-Escudero P, Martinez-Rodriguez P, Gomez-Pando LR, ..., Gandia-Herrero F*.
Formation of carboxylated and decarboxylated betalains in ripening grains of Chenopodium quinoa by a dual dioxygenase.
Journal of Experimental Botany, 2022, 73, 4170-4183, PMID: 35390139, FI: 6.9
Monteagudo-Cascales E, Martin-Mora D, Xu W, ..., Ortega A et al.
The pH Robustness of Bacterial Sensing.
Mbio, 2022, 13, e0165022, PMID: 36154178, FI: 6.4
Navarro-Serna S, Pineiro-Silva C, Luongo C, ..., Gadea J.
Effect of Aphidicolin, a Reversible Inhibitor of Eukaryotic Nuclear DNA Replication, on the Production of Genetically Modified Porcine Embryos by CRISPR/Cas9.
, 2022, 23, PMID: 35216252, FI: 6.208
Lopes JS, Ivanova E, Ruiz S, ..., Coy P.
Effect of Superovulation Treatment on Oocyte's DNA Methylation.
, 2022, 23, PMID: 36555801, FI: 6.208
Guadarrama-Flores B, Matencio A, Navarro-Orcajada S, ..., Lopez-Nicolas JM.
Development if healthy milk and yogurt products for reducing metabolic diseases using cyclodextrin and omega-3 fatty acids from fish oil.
Food & Function, 2022, 13, 5528-5535, PMID: 35522849, FI: 6.1
Navarro-Orcajada S, Conesa I, Matencio A, ..., Lopez-Nicolas JM.
The use of cyclodextrins as solubility enhancers in the ORAC method may cause interference in the measurement of antioxidant activity.
Talanta, 2022, 243, 123336, PMID: 35240366, FI: 6.1
Gea-Gonzalez A, Hernandez-Garcia S*, Henarejos-Escudero P, ..., Gandia-Herrero F*.
Polyphenols from traditional Chinese medicine and Mediterranean diet are effective against Abeta toxicity in vitro and in vivo in Caenorhabditis elegans.
Food & Function, 2022, 13, 1206-1217, PMID: 35018947, FI: 6.1
Bernabe-Diaz JA, Franco M, Vivo JM, ..., Fernandez-Breis JT*.
An automated process for supporting decisions in clustering-based data analysis.
Computer Methods and Programs in Biomedicine, 2022, 219, 106765, PMID: 35367914, FI: 6.1
Mulero Hernandez J, Fernandez-Breis JT*.
Analysis of the landscape of human enhancer sequences in biological databases.
Computational and Structural Biotechnology Journal, 2022, 20, 2728-2744, PMID: 35685360, FI: 6.0
Sanchez-Villalobos JM*, Aledo-Serrano A, Villegas-Martinez I, ..., Alcaraz M*.
Epilepsy treatment in neuro-oncology: A rationale for drug choice in common clinical scenarios.
, 2022, 13, 991244, PMID: 36278161, FI: 5.988
Luongo C, Llamas-Lopez PJ, Hernandez-Caravaca I, ..., Garcia-Vazquez FA.
Should All Fractions of the Boar Ejaculate Be Prepared for Insemination Rather Than Using the Sperm Rich Only?
, 2022, 11, PMID: 35205077, FI: 5.168
Ferri JM, Aldas M, Rayon E, ..., Lozano-Perez AA.
The Influence of Different Sustainable Silk-Based Fillers on the Thermal and Mechanical Properties of Polylactic Acid Composites.
, 2022, 14, PMID: 36433143, FI: 4.967
Asensio Ruiz MA, Fuster MG, Martinez Martinez T, ..., Lozano-Perez AA.
The Effect of Sterilization on the Characteristics of Silk Fibroin Nanoparticles.
, 2022, 14, PMID: 35160487, FI: 4.967
Sanchez-Romero J, Lopez-Perez J, Flores-Munoz AB, ..., Sanchez-Ferrer ML.
Sedation with Propofol plus Paracetamol in External Cephalic Version: An Observational Study.
, 2022, 11, PMID: 35159941, FI: 4.964
Hcini K, Bahi A, Zarroug MB, ..., Lozano-Perez AA et al.
Polyphenolic Profile of Tunisian Thyme (Thymbra capitata L.) Post-Distilled Residues: Evaluation of Total Phenolic Content and Phenolic Compounds and Their Contribution to Antioxidant Activity.
, 2022, 27, PMID: 36557924, FI: 4.927
Kuiper M, Bonello J, Fernandez-Breis JT et al.
The gene regulation knowledge commons: the action area of GREEKC.
Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, 2022, 1865, 194768, PMID: 34757206, FI: 4.7
Navarro-Orcajada S, Conesa I, Matencio A, ..., Lopez-Nicolas JM.
Molecular encapsulation and bioactivity of gnetol, a resveratrol analogue, for use in foods.
Journal of the Science of Food and Agriculture, 2022, 102, 4296-4303, PMID: 35043401, FI: 4.1
Vazquez MB, Matencio A, Bianchinotti MV, ..., Lopez-Nicolas JM.
Enhanced production of 2-phenylethanol by salicylic acid and cyclodextrins in cell suspension cultures of the unexplored filamentous fungus Monochaetinula geoffroeana.
Journal of the Science of Food and Agriculture, 2022, 102, 1609-1618, PMID: 34405402, FI: 4.1
Sola-Martinez RA*, Sanchez-Solis M, Lozano-Terol G, ..., de Diego Puente T*.
Relationship between lung function and exhaled volatile organic compounds in healthy infants.
, 2022, 10.1002/ppul.25849 [doi], PMID: 35092361, FI: 4.09
Gonzalez-Lopez A*.
Technical note: Characteristics of the energy spread kernels of scattered radiation in an x-ray room.
Medical Physics, 2022, 10.1002/mp.15891 [doi], PMID: 35908179, FI: 3.8
Ortega A, Matilla MA, Krell T.
The Repertoire of Solute-Binding Proteins of Model Bacteria Reveals Large Differences in Number, Type, and Ligand Range.
Microbiology Spectrum, 2022, 10, e0205422, PMID: 36121253, FI: 3.7
Ataman-Millhouse LM, Monahan P, Willingham R, ..., Gadea J et al.
Broadening the educational pipeline: the global landscape of master of science programs in reproductive science and medicine.
Biology of Reproduction, 2022, 107, 664-675, PMID: 35639631, FI: 3.6
Gonzalez-Plaza A, Cambra JM, Parrilla I, ..., Martinez CA*, Cuello C*.
The Open Cryotop System Is Effective for the Simultaneous Vitrification of a Large Number of Porcine Embryos at Different Developmental Stages.
, 2022, 9, 936753, PMID: 35812891, FI: 3.471
Gonzalez-Ramiro H, Parrilla I, Miquel Cambra J, ..., Martinez CA*.
Combined synchronization and superovulation treatments negatively impact embryo viability possibly by the downregulation of WNT/beta-catenin and Notch signaling genes in the porcine endometrium.
Journal of Animal Science, 2022, 100, PMID: 36169657, FI: 3.3
Beltran-Frutos E, Seco-Rovira V, Martinez-Hernandez J, ..., Pastor LM*.
Cellular Modifications in Spermatogenesis during Seasonal Testicular Regression: An Update Review in Mammals.
Animals, 2022, 12, PMID: 35804504, FI: 3.0
Romero-Aguirregomezcorta J, Ramirez LL, Ortin A, ..., Coy P.
Differences in Weight, Hierarchy, and Incidence of Lameness between Two Groups of Adult Pigs Derived from Assisted Reproductive Technologies.
Animals, 2022, 12, PMID: 36552498, FI: 3.0
Moya-Jodar M, Coppiello G, Rodriguez-Madoz JR, ..., Navarro-Serna S et al.
One-Step In Vitro Generation of ETV2-Null Pig Embryos.
Animals, 2022, 12, PMID: 35883376, FI: 3.0
Mckensy-Sambola Dexon, Rodriguez-Garcia Miguel Angel, Garcia-Sanchez Francisco, Valencia-Garcia Rafael*.
Ontology-Based Nutritional Recommender System
, 2022, 12, PMID: null, FI: 2.838
Picazo CM, Castano C, Boveda P, ..., Gadea J et al.
Cryopreservation of testicular tissue from the dog (Canis familiaris) and wild boar (Sus scrofa) by slow freezing and vitrification: Differences in cryoresistance according to cell type.
Theriogenology, 2022, 190, 65-72, PMID: 35963122, FI: 2.8
Navarro-Serna S, Dehesa-Etxebeste M, Pineiro-Silva C, ..., Gadea J.
Generation of Calpain-3 knock-out porcine embryos by CRISPR-Cas9 electroporation and intracytoplasmic microinjection of oocytes before insemination.
Theriogenology, 2022, 186, 175-184, PMID: 35500431, FI: 2.8
Ruiz S, Gardon JC, Hernandez-Caravaca I, ..., Garcia-Vazquez FA.
Analysis of Uterine Blood Flow in Breeding Sows through the Estrus and Early Diestrus, and after Artificial Insemination.
, 2022, 9, PMID: 35737312, FI: 2.518
Lopez-Ubeda R, Garcia-Vazquez FA.
Self-directed learning using computer simulations to study veterinary physiology: Comparing individual and collaborative learning approaches.
Veterinary Record, 2022, 191, e1732, PMID: 35634718, FI: 2.2
van Damme P, Fernandez-Breis JT, Benis N, Minarro-Gimenez JA et al.
Performance assessment of ontology matching systems for FAIR data.
Journal of Biomedical Semantics, 2022, 13, 19, PMID: 35841031, FI: 1.9
Diaz LS, Navalon CI, Espin RG et al.
[Not Available].
Gastroenterologia y Hepatologia, 2022, S0210-5705(22)00265-5 [pii], PMID: 36400260, FI: 1.9
Paris-Oller E, Soriano-Ubeda C, Belda-Perez R, ..., Coy P.
Reproductive fluids, added to the culture media, contribute to minimizing phenotypical differences between in vitro-derived and artificial insemination-derived piglets.
Journal of Developmental Origins of Health and Disease, 2022, , 1-13, PMID: 34986913, FI: 1.7
Coy P, Romar R, Romero-Aguirregomezcorta J.
The embryo culture media in the era of epigenetics: is it time to go back to nature?
Animal Reproduction, 2022, 19, e20210132, PMID: 35493788, FI: 1.7
Gonzalez-Plaza A, Brullo C, Cambra JM, ..., Cuello C*.
Equilibration time with cryoprotectants, but not melatonin supplementation during in vitro maturation, affects viability and metaphase plate morphology of vitrified porcine mature oocytes.
Reproduction in Domestic Animals, 2022, 57 Suppl 5, 58-63, PMID: 35567517, FI: 1.7
Parrilla I*, Gil MA, Cuello C, ..., Martinez EA.
Immunological uterine response to pig embryos before and during implantation.
Reproduction in Domestic Animals, 2022, 57 Suppl 5, 4-13, PMID: 35500162, FI: 1.7
Parrilla I, Rodriguez-Martinez H, Cuello C, ..., Martinez EA*.
Neither frozen-thawed seminal plasma nor commercial transforming growth factor-beta1 infused intra-utero before insemination improved fertility and prolificacy in sows.
Reproduction in Domestic Animals, 2022, 57 Suppl 5, 86-89, PMID: 35467050, FI: 1.7
AYUDAS CONCEDIDAS EN 2022
TOTAL DE AYUDAS CONCEDIDAS
9
Nº Ayudas
1.44M €
Financiación
TOTAL DE AYUDAS RECURSOS HUMANOS CONCEDIDAS
1
Nº Ayudas
0.07M €
Financiación
TOTAL DE AYUDAS PROYECTOS I+D+i CONCEDIDAS
2
Nº Ayudas Europeas
0.39M €
Financiación Europea
5
Nº Ayudas Nacionales
0.89M €
Financiación Nacional
1
Nº Ayudas Regionales
0.1M €
Financiación Regional
TOTAL DE REDES CONCEDIDAS
0
Nº Ayudas
0.0M €
Financiación
OTRAS AYUDAS COMPETITIVAS CONCEDIDAS (MOVILIDAD, ORGANIZACIÓN DE EVENTOS CIENTÍFICOS, ...)
0
Nº Ayudas
0.0K €
Financiación
PROYECTOS DE I+D+i Y AYUDAS DE RRHH ACTIVAS EN 2022
27
TOTAL AYUDAS
2
RECURSOS HUMANOS
0
REDES
4
PROYECTOS INTERNACIONALES
13
PROYECTOS NACIONALES
8
PROYECTOS REGIONALES
INICIADA EN 2022
3
Nº Estudios
1
Nº Ensayos Clínicos
0
Nº Producto Sanitario
0
Nº Estudios Post-Autorización
2
Nº Otros Estudios
ACTIVOS EN 2022
8
Nº Estudios
3
Nº Ensayos Clínicos
1
Nº Producto Sanitario
0
Nº Estudios Post-Autorización
4
Nº Otros Estudios
FACTURACIÓN EN 2022
0.05M €
Facturado
12
Nº Tesis (0 con mención internacional)
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