MEMORIA 2022 - Área 2. Enfermedades Cardiovasculares y Respiratorias

Área 2. Enfermedades Cardiovasculares y Respiratorias

OBJETIVOS CIENTÍFICOS VINCULADOS AL PLAN ESTRATÉGICO

Generar conocimiento científico de excelencia: los números del Área son muy similares a 2021 incrementando levemente el número de trabajos publicados aunque en revistas de menor impacto. Los indicadores de liderazgo nos indican claramente que el liderazgo científico ha aumentado considerablemente con respecto al año anterior, liderando el 50% de los trabajos publicados.
Captación de talento científico: la captación de recursos humanos es notablemente mejor que la de años anteriores consiguiendo tres ayudas competitivas. También hay un crecimiento importante en el personal de apoyo a la investigación financiado con proyectos tanto competitivos como con no competitivos.
Dinamizar la captación de recursos: la captación de recursos competitivos ha crecido notablemente con respecto al anterior gracias a la concesión de un proyecto de medicina de precisión con un presupuesto aproximado de tres millones de euros y en el que participan 70 hospitales de toda España, relacionado con Miocarditis. Sin embargo, la facturación por estudios de investigación clínica y en contratos de investigación privados se ha visto reducida.

7 Grupos de Investigación

CARDIOLOGIA CLINICA Y EXPERIMENTAL (CONSOLIDADO)
INVESTIGACIÓN EN PEDIATRÍA (CONSOLIDADO)
TERAPIAS RESPIRATORIAS EN LA INSUFICIENCIA RESPIRATORIA AGUDA (CLÍNICO ASOCIADO)
AEROBIOLOGÍA Y TOXICOLOGÍA AMBIENTAL (EMERGENTE)
FISIOLOGÍA MÉDICA (EMERGENTE)
GRUPO DE INVESTIGACIÓN DE ENFERMERÍA EN AVANCES EN PRUEBAS FUNCIONALES RESPIRATORIAS (CLÍNICO ASOCIADO)
INVESTIGACIÓN Y DESARROLLO EN CIRUGÍA CARDIOVASCULAR (CLÍNICO ASOCIADO)

INDICADORES GENERALES

111

Nº Publicaciones

917.05

Impacto Total

8.26

Impacto Medio

Tipo	Nº Pubs	FI total	FI Medio
Originales	104 (93.69%)	881.05	8.47
Revisiones	7 (6.31%)	36.0	5.14

55.86

Q1%

17.12

D1%

FI >= 15

Tipo	Nº Q1	Nº D1	Nº FI >= 15
Originales	59	18	9
Revisiones	3	1	0

INDICADORES DE LIDERAZGO

55 (50.0%)

Nº Publicaciones

291.52

Impacto Total

5.3

Impacto Medio

	Nº Pubs	FI total	FI Medio
Mujer	16 (29.09%)	82.17	5.14
Hombre	39 (70.91%)	209.35	5.37

45.45

Q1%

10.91

D1%

FI >= 15

	Nº Q1	Nº D1	Nº FI >= 15
Mujer	8	2	0
Hombre	17	4	2

OTROS INDICADORES

34.59

HCP10% (2018-2022)

25.45

HCP10 Liderado% (2018-2022)

10.3

HCP10 Lid. Mujeres% (2018-2022)

4.33

Crown (2018-2022)

59.46

Open Access%

62.16

Col. International%

* Se muestran las 5 especies, los 10 genes y las 20 enfermedades más nombradas. Los valores están normalizados logarítmicamente en base al número de publicaciones.

INDICADORES EVOLUTIVOS

DESTACADAS

Garcia-Marcos L*, Innes Asher M, Pearce N et al. The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study. European Respiratory Journal, 2022, 2102866 [pii], PMID: 35144987, FI: 24.3

Palau P, Amiguet M, Dominguez E, ..., Pascual-Figal D* et al. COLABORADORES: Palau P, Amiguet M, Dominguez E, ..., Pascual-Figal D et al. Short-term effects of dapagliflozin on maximal functional capacity in heart failure with reduced ejection fraction (DAPA-VO(2) ): a randomized clinical trial. European Journal of Heart Failure, 2022, 24, 1816-1826, PMID: 35604416, FI: 18.2

Esteve-Pastor MA*, Rivera-Caravaca JM, Roldan V, ..., Marin F*. Predicting performance of the HAS-BLED and ORBIT bleeding risk scores in patients with atrial fibrillation treated with Rivaroxaban: Observations from the prospective EMIR Registry. , 2022, pvac060 [pii], PMID: 36318457, FI: 11.177

Ramirez-Macias I, Orenes-Pinero E, Camelo-Castillo A, ..., Marin F. Novel insights in the relationship of gut microbiota and coronary artery diseases. Critical Reviews in Food Science and Nutrition, 2022, 62, 3738-3750, PMID: 33399007, FI: 10.2

Sanchez-Camara S, Asensio-Lopez MC, Royo-Villanova M, ..., Pinar E*, ..., Pascual-Figal DA*. Critical warm ischemia time point for cardiac donation after circulatory death. American Journal of Transplantation, 2022, 22, 1321-1328, PMID: 35114047, FI: 8.8

LISTADO COMPLETO

Castellano JM, Pocock SJ, Bhatt DL, ..., Marin Ortuno F et al. Polypill Strategy in Secondary Cardiovascular Prevention. New England Journal of Medicine, 2022, 387, 967-977, PMID: 36018037, FI: 158.5

Protonotarios A, Bariani R, Cappelletto C, ..., Gimeno JR et al. Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculator. European Heart Journal, 2022, ehac235 [pii], PMID: 35766183, FI: 39.3

Rao SV, Kirsch B, Bhatt DL et al. COLABORADORES: Hengstenberg C, Steinwender C, Alber H, ..., Pascual-Figal D et al. A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction. Circulation, 2022, 146, 1196-1206, PMID: 36030390, FI: 37.8

Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, ..., Sabater-Molina M et al. Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation, 2022, 10.1161/CIRCULATIONAHA.121.058767 [doi], PMID: 36325906, FI: 37.8

Barc J, Tadros R, Glinge C, ..., Ortuno CG et al. Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nature Genetics, 2022, 10.1038/s41588-021-01007-6 [doi], PMID: 35210625, FI: 30.8

Mortimer K, Lesosky M, Garcia-Marcos L et al. The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study. European Respiratory Journal, 2022, 2102865 [pii], PMID: 35210319, FI: 24.3

de Frutos F, Ochoa JP, Navarro-Penalver M, ..., Sabater-Molina M et al. Natural History of MYH7-Related Dilated Cardiomyopathy. Journal of the American College of Cardiology, 2022, 80, 1447-1461, PMID: 36007715, FI: 24.0

Ammirati E, Raimondi F, Piriou N, ..., Gil C et al. Acute Myocarditis Associated With Desmosomal Gene Variants. Jacc-Heart Failure, 2022, 10, 714-727, PMID: 36175056, FI: 13.0

Rouhi L, Fan S, Cheedipudi SM, ..., Molina MS et al. The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure. Cardiovascular Research, 2022, 118, 1466-1478, PMID: 34132777, FI: 10.8

Romiti GF, Proietti M, Vitolo M, ..., Marin F et al. Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry. Bmc Medicine, 2022, 20, 326, PMID: 36056426, FI: 9.3

Norrish G, Topriceanu C, Qu C, ..., Gimeno JR et al. The role of the electrocardiographic phenotype in risk stratification for sudden cardiac death in childhood hypertrophic cardiomyopathy. European Journal of Preventive Cardiology, 2022, 29, 645-653, PMID: 33772274, FI: 8.3

Boriani G, Vitolo M, Malavasi VL, ..., Marin F et al. Impact of anthropometric factors on outcomes in atrial fibrillation patients: analysis on 10 220 patients from the European Society of Cardiology (ESC)-European Heart Rhythm Association (EHRA) EurObservational Research Programme on Atrial Fibrillation (EORP-AF) general long-term registry. European Journal of Preventive Cardiology, 2022, 29, 1967-1981, PMID: 35671129, FI: 8.3

Vitolo M, Malavasi VL, Proietti M, ..., Marin F et al. Cardiac troponins and adverse outcomes in European patients with atrial fibrillation: A report from the ESC-EHRA EORP atrial fibrillation general long-term registry. European Journal of Internal Medicine, 2022, 99, 45-56, PMID: 35177307, FI: 8.0

Ding WY, Kotalczyk A, Boriani G, Marin F et al. Impact of diabetes on the management and outcomes in atrial fibrillation: an analysis from the ESC-EHRA EORP-AF Long-Term General Registry. European Journal of Internal Medicine, 2022, 103, 41-49, PMID: 35527179, FI: 8.0

Vitolo M, Proietti M, Malavasi VL, ..., Marin F et al. Adherence to the "Atrial fibrillation Better Care" (ABC) pathway in patients with atrial fibrillation and cancer: A report from the ESC-EHRA EURObservational Research Programme in atrial fibrillation (EORP-AF) General Long-Term Registry. European Journal of Internal Medicine, 2022, 105, 54-62, PMID: 36028394, FI: 8.0

Ding WY, Proietti M, Romiti GF, ..., Marin F et al. Impact of ABC (Atrial Fibrillation Better Care) pathway adherence in high-risk subgroups with atrial fibrillation: A report from the ESC-EHRA EORP-AF long-term general registry. European Journal of Internal Medicine, 2022, S0953-6205(22)00387-9 [pii], PMID: 36372692, FI: 8.0

Santoyo JM, Noguera JA, Aviles F, ..., Hernandez I*. Factors Involved in Endothelial Dysfunction Related to Angiogenic Disbalance and Oxidative Stress, in Women at High Risk of Term Pre-Eclampsia. , 2022, 11, PMID: 35883900, FI: 7.675

Martinez-Montesinos L, Rivera-Caravaca JM*, Agewall S, ..., Roldan V*. Polypharmacy and adverse events in atrial fibrillation: Main cause or reflection of multimorbidity? Biomedicine & Pharmacotherapy, 2022, 158, 114064, PMID: 36495662, FI: 7.5

Rossello X, Raposeiras-Roubin S, Latini R, ..., Pascual-Figal D et al. Rationale and design of the pragmatic clinical trial tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion (REBOOT). European Heart Journal-Cardiovascular Pharmacotherapy, 2022, 8, 291-301, PMID: 34351426, FI: 7.1

Nadarajah R, Ludman P, Appelman Y et al. COLABORADORES: Vahanian A, Budaj A, Dagres N, ..., Marin F et al. Cohort profile: the ESC EURObservational Research Programme Non-ST-segment elevation myocardial infraction (NSTEMI) Registry. , 2022, 9, 8-15, PMID: 36259751, FI: 7.064

Patti G, D'Ascenzo F, De Filippo O, ..., Manzano-Fernandez S* et al. Safety and efficacy of different P2Y12 inhibitors in patients with acute coronary syndromes stratified by the PRAISE risk score: a multicentre study. , 2022, 8, 881-891, PMID: 35022719, FI: 7.064

Carrillo-Aleman L, Lopez-Martinez A, Carrillo-Alcaraz A, ..., Pascual-Figal D*. Outcome of patients with acute heart failure secondary to acute myocardial infarction treated with noninvasive mechanical ventilation. Revista Espanola de Cardiologia, 2022, 75, 50-59, PMID: 33257215, FI: 6.975

Bermudez-Jimenez FJ, Carriel V, Santos-Mateo JJ, ..., Gimeno Blanes JR et al. ROD2 domain filamin C missense mutations exhibit a distinctive cardiac phenotype with restrictive/hypertrophic cardiomyopathy and saw-tooth myocardium. Revista Espanola de Cardiologia, 2022, S1885-5857(22)00210-9 [pii], PMID: 35952944, FI: 6.975

Alvarez Rubio J, Manovel Sanchez AJ, Gonzalez-Costello J, ..., Gimeno Blanes JR et al. Characterization of hereditary transthyretin cardiac amyloidosis in Spain. Revista Espanola de Cardiologia, 2022, 75, 488-495, PMID: 34711514, FI: 6.975

Gorog DA, Gue YX, Chao TF, ..., Roldan V et al. Assessment and Mitigation of Bleeding Risk in Atrial Fibrillation and Venous Thromboembolism: Executive Summary of a European and Asia-Pacific Expert Consensus Paper. Thrombosis and Haemostasis, 2022, 122, 1625-1652, PMID: 35793691, FI: 6.7

Romiti GF, Pastori D, Rivera-Caravaca JM et al. Adherence to the 'Atrial Fibrillation Better Care' Pathway in Patients with Atrial Fibrillation: Impact on Clinical Outcomes-A Systematic Review and Meta-Analysis of 285,000 Patients. Thrombosis and Haemostasis, 2022, 122, 406-414, PMID: 34020488, FI: 6.7

Proietti M, Romiti GF, Vitolo M, ..., Marin F et al. Epidemiology and impact of frailty in patients with atrial fibrillation in Europe. Age and Ageing, 2022, 51, PMID: 35997262, FI: 6.7

Santoro F, Nunez-Gil IJ, Vitale E, ..., Marin F et al. Aspirin Therapy on Prophylactic Anticoagulation for Patients Hospitalized With COVID-19: A Propensity Score-Matched Cohort Analysis of the HOPE-COVID-19 Registry. , 2022, 11, e024530, PMID: 35730631, FI: 6.106

Ding WY, Proietti M, Boriani G, ..., Marin F et al. Clinical utility and prognostic implications of the novel 4S-AF scheme to characterize and evaluate patients with atrial fibrillation: a report from ESC-EHRA EORP-AF Long-Term General Registry. Europace, 2022, 24, 721-728, PMID: 35446354, FI: 6.1

Rivera-Caravaca JM*, Badimon L, Ferreira-Gonzalez I, ..., Marin F*. Variables affecting the quality of anticoagulation in atrial fibrillation patients newly initiating vitamin K antagonists: insights from the national and multicentre SULTAN registry. Europace, 2022, 24, 4-11, PMID: 34115857, FI: 6.1

Rivera-Caravaca JM, Piot O, Roldan-Rabadan I, ..., Marin F*. Characterization of atrial fibrillation in real-world patients: testing the 4S-AF scheme in the Spanish and French cohorts of the EORP-AF Long-Term General Registry. Europace, 2022, 24, 202-210, PMID: 34374759, FI: 6.1

Ding WY, Blomstrom-Lundqvist C, Fauchier L, Marin F et al. Contemporary management of atrial fibrillation and the predicted vs. absolute risk of ischaemic stroke despite treatment: a report from ESC-EHRA EORP-AF Long-Term General Registry. Europace, 2022, euac214 [pii], PMID: 36427202, FI: 6.1

Khan A, Iqtadar S, Mumtaz SU, ..., Pascual-Figal DA* et al. Oral Co-Supplementation of Curcumin, Quercetin, and Vitamin D3 as an Adjuvant Therapy for Mild to Moderate Symptoms of COVID-19-Results From a Pilot Open-Label, Randomized Controlled Trial. , 2022, 13, 898062, PMID: 35747751, FI: 5.988

Hernandez-Vaquero D, Rodriguez-Caulo E, Vigil-Escalera C, ..., Canovas S et al. Life expectancy after aortic valve replacement in young patients. Revista Espanola de Cardiologia, 2022, 75, 294-299, PMID: 34103259, FI: 5.9

Rodriguez-Manero M, Baluja A, Hernandez J, Munoz C et al. Validation of multiparametric approaches for the prediction of sudden cardiac death in patients with Brugada syndrome and electrophysiological study. Revista Espanola de Cardiologia, 2022, 75, 559-567, PMID: 34479845, FI: 5.9

Pinar E*, Garcia de Lara J*, Hurtado J*, ..., Leithold G* et al. Cost-effectiveness analysis of the SAPIEN 3 transcatheter aortic valve implant in patients with symptomatic severe aortic stenosis. Revista Espanola de Cardiologia, 2022, 75, 325-333, PMID: 34016548, FI: 5.9

Martinez-Solano J, Ortiz-Bautista C, Gutierrez-Ibanes E, ..., Garcia-Lara J* et al. Optical coherence tomography assessment of pulmonary vascular remodeling in advanced heart failure. The OCTOPUS-CHF study. Revista Espanola de Cardiologia, 2022, S1885-5857(22)00240-7 [pii], PMID: 36155847, FI: 5.9

Diego-Nieto A, Nunez JC, Minana G, ..., Lacunza J* et al. Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions. Revista Espanola de Cardiologia, 2022, S1885-5857(22)00140-2 [pii], PMID: 35691552, FI: 5.9

Rodriguez-Leor O, Cid-Alvarez AB, Perez de Prado A, ...,Lopez-Palop R et al. Analysis of the management of ST-segment elevation myocardial infarction in Spain. Results from the ACI-SEC Infarction Code Registry. Revista Espanola de Cardiologia, 2022, 75, 669-680, PMID: 35067471, FI: 5.9

Fawzy AM, Rivera-Caravaca JM, Underhill P et al. Incident heart failure, arrhythmias and cardiovascular outcomes with sodium-glucose cotransporter 2 (SGLT2) inhibitor use in patients with diabetes: Insights from a global federated electronic medical record database. Diabetes Obesity & Metabolism, 2022, 10.1111/dom.14854 [doi], PMID: 36054168, FI: 5.8

Cimci M, Polad J, Mamas M et al. COLABORADORES: Mendiz O, Telayna JM, Magni J, ..., Pinar E et al. Outcomes and regional differences in practice in a worldwide coronary stent registry. Heart, 2022, 108, 1310-1318, PMID: 35012960, FI: 5.7

Rivera-Caravaca JM, Roldan V*, Martinez-Montesinos L, ..., Marin F. The Atrial Fibrillation Better Care (ABC) Pathway and Clinical Outcomes in Patients with Atrial Fibrillation: the Prospective Murcia AF Project Phase II Cohort. Journal of General Internal Medicine, 2022, 10.1007/s11606-022-07567-5 [doi], PMID: 35411538, FI: 5.7

Santoro F, Nunez-Gil IJ, Vitale E, ..., Marin F et al. Antiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation Registry. Heart, 2022, 108, 130-136, PMID: 34611045, FI: 5.7

Rodriguez-Leor O, de la Torre Hernandez JM, Garcia-Camarero T, ..., Pinar E* et al. Instantaneous Wave-Free Ratio for the Assessment of Intermediate Left Main Coronary Artery Stenosis: Correlations With Fractional Flow Reserve/Intravascular Ultrasound and Prognostic Implications: The iLITRO-EPIC07 Study. Circulation-Cardiovascular Interventions, 2022, 15, 861-871, PMID: 36111801, FI: 5.6

Ding WY, Potpara TS, Blomstrom-Lundqvist C et al. COLABORADORES: Boriani G, Lip GYH, Tavazzi L, ..., Marin F et al. Impact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry. European Journal of Clinical Investigation, 2022, , e13745, PMID: 35000206, FI: 5.5

Malavasi VL, Vitolo M, Proietti M, ..., Marin F et al. Impact of malignancy on outcomes in European patients with atrial fibrillation: A report from the ESC-EHRA EURObservational research programme in atrial fibrillation general long-term registry. European Journal of Clinical Investigation, 2022, , e13773, PMID: 35305020, FI: 5.5

Chalkias A, Skoulakis A, Papagiannakis N, ..., Bernal-Morell E et al. Circulating suPAR associates with severity and in-hospital progression of COVID-19. European Journal of Clinical Investigation, 2022, 52, e13794, PMID: 35435245, FI: 5.5

Lopez-Galvez R, Rivera-Caravaca JM, Anguita Sanchez M, ..., Marin F*. Use of rivaroxaban attenuates renal function impairment in patients with atrial fibrillation: insights of the EMIR study. European Journal of Clinical Investigation, 2022, 52, e13788, PMID: 35395094, FI: 5.5

Perez Cabeza AI, Rivera-Caravaca JM, Roldan-Rabadan I, ..., Marin F*. Antithrombotic therapy and clinical outcomes at 1 year in the Spanish cohort of the EORP-AF Long-term General Registry. European Journal of Clinical Investigation, 2022, 52, e13709, PMID: 34757635, FI: 5.5

Fleurot I, Lopez-Galvez R*, Barbry P et al. TLR5 signalling is hyper-responsive in porcine cystic fibrosis airways epithelium. Journal of Cystic Fibrosis, 2022, 21, e117-e121, PMID: 34420900, FI: 5.2

Lopes LR, Losi MA, Sheikh N, ..., Gimeno J et al. Association Between Common Cardiovascular Risk Factors and Clinical Phenotype in Patients with Hypertrophic Cardiomyopathy From the European Society of Cardiology (ESC) EurObservational Research Programme (EORP) Cardiomyopathy/Myocarditis Registry. European Heart Journal-Quality of Care and Clinical Outcomes, 2022, qcac006 [pii], PMID: 35138368, FI: 5.2

Morales E*, Garcia-Serna AM, Larque E, ..., Garcia-Marcos L*. Dietary Patterns in Pregnancy and Biomarkers of Oxidative Stress in Mothers and Offspring: The NELA Birth Cohort. Frontiers in Nutrition, 2022, 9, 869357, PMID: 35495932, FI: 5.0

Ding WY, Rivera-Caravaca JM, Fazio-Eynullayeva E et al. Outcomes of left atrial appendage occlusion vs. non-vitamin K antagonist oral anticoagulants in atrial fibrillation. Clinical Research in Cardiology, 2022, 10.1007/s00392-021-01983-z [doi], PMID: 34994832, FI: 5.0

Proietti M, Vitolo M, Harrison SL, ..., Marin F et al. Real-world applicability and impact of early rhythm control for European patients with atrial fibrillation: a report from the ESC-EHRA EORP-AF Long-Term General Registry. Clinical Research in Cardiology, 2022, 111, 70-84, PMID: 34448931, FI: 5.0

Delgado-Jimenez JF, Segovia-Cubero J, Almenar-Bonet L, ..., Pascual-Figal DA* et al. Prevalence, Incidence, and Outcomes of Hyperkalaemia in Patients with Chronic Heart Failure and Reduced Ejection Fraction from a Spanish Multicentre Study: SPANIK-HF Design and Baseline Characteristics. , 2022, 11, PMID: 35268260, FI: 4.964

Valles E, Jimenez J, Marti-Almor J, ..., Garcia-Alberola A* et al. Cryoballoon Ablation for Persistent and Paroxysmal Atrial Fibrillation: Procedural Differences and Results from the Spanish Registry (RECABA). , 2022, 11, PMID: 35268259, FI: 4.964

Lopez-Galvez R, Rivera-Caravaca JM, Roldan V, ..., Marin F. Imaging in atrial fibrillation: A way to assess atrial fibrosis and remodeling to assist decision-making. American Heart Journal, 2022, 258, 1-16, PMID: 36526006, FI: 4.8

Reverte V, Rodriguez F, Oltra L et al. SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet. American Journal of Physiology-Heart and Circulatory Physiology, 2022, 322, H523-H536, PMID: 35119333, FI: 4.8

Garcia-Tudela A, Simonelli-Munoz AJ, Rivera-Caravaca JM et al. Stress in Emergency Healthcare Professionals: The Stress Factors and Manifestations Scale. , 2022, 19, PMID: 35410024, FI: 4.614

Melgarejo-Meseguer FM, Everss-Villalba E, Gutierrez-Fernandez-Calvillo M, ..., Garcia-Alberola A et al. Generalization and Regularization for Inverse Cardiac Estimators. Ieee Transactions on Biomedical Engineering, 2022, 69, 3029-3038, PMID: 35294340, FI: 4.6

Martinez-Solano J, Gutierrez-Ibanes E, Ortiz-Bautista C, ..., Garrido-Bravo IP* et al. Pulmonary Vascular Remodeling and Prognosis in Patients Evaluated for Heart Transplantation: Insights from the OCTOPUS-CHF Study. , 2022, 9, PMID: 36547436, FI: 4.415

Garcia-Serna AM, Martin-Orozco E, Jimenez-Guerrero P, ..., Morales E*. Cytokine profiles in cord blood in relation to prenatal traffic-related air pollution: The NELA cohort. Pediatric Allergy and Immunology, 2022, 33, e13732, PMID: 35212052, FI: 4.4

Strachan DP, Rutter CE, Asher MI, ..., Garcia-Marcos L et al. Worldwide time trends in prevalence of symptoms of rhinoconjunctivitis in children: Global Asthma Network Phase I. Pediatric Allergy and Immunology, 2022, 33, e13656, PMID: 34453861, FI: 4.4

Chiang CY, Ellwood P, Ellwood E, Garcia-Marcos L et al. Infection with SARS-CoV-2 among children with asthma: evidence from Global Asthma Network. Pediatric Allergy and Immunology, 2022, 33, e13709, PMID: 34856034, FI: 4.4

Blanco-Morillo J*, Salmeron Martinez D, Morillo-Cuadrado DV, ..., Canovas-Lopez S*. Hematic Antegrade Repriming Reduces Emboli on Cardiopulmonary Bypass: A Randomized Controlled Trial. Asaio Journal, 2022, 10.1097/MAT.0000000000001776 [doi], PMID: 35609139, FI: 4.2

Antonogeorgos G, Liakou E, Koutsokera A, ..., Garcia-Marcos L et al. Parental education moderates the association between indoor moisture environment and asthma in adolescents: the Greek Global Asthma Network (GAN) cross-sectional study. , 2022, 22, 597, PMID: 35346139, FI: 4.135

Garcia-Marcos L*, Chiang CY, Silverwood R et al. Global Asthma Management and Control. International Journal of Tuberculosis and Lung Disease, 2022, 26, 29-31, PMID: 36284433, FI: 4.0

Mortimer K, Bissell K, Cruz A, Garcia-Marcos L et al. Asthma in the Context of Other Chronic Respiratory Diseases in LMICs. International Journal of Tuberculosis and Lung Disease, 2022, 26, 74-75, PMID: 36284430, FI: 4.0

Ellwood P, Asher I, Bissell K, ..., Garcia-Marcos L et al. Asthma Network. International Journal of Tuberculosis and Lung Disease, 2022, 26, 14-15, PMID: 36284425, FI: 4.0

Garcia-Marcos L*. Asthma in the European region. International Journal of Tuberculosis and Lung Disease, 2022, 26, 56-60, PMID: 36284423, FI: 4.0

Chiang CY, Crossingham I, Sony AE, ..., Garcia-Marcos L et al. New Approaches with Asthma Medicines. International Journal of Tuberculosis and Lung Disease, 2022, 26, 72-73, PMID: 36284420, FI: 4.0

Rutter C, Silverwood R, Perez Fernandez V, ..., Garcia-Marcos L*. The Global Burden of Asthma. International Journal of Tuberculosis and Lung Disease, 2022, 26, 20-23, PMID: 36284412, FI: 4.0

Pearce N, Garcia-Marcos L, Morales E et al. Asthma and Factors Affecting it. International Journal of Tuberculosis and Lung Disease, 2022, 26, 16-19, PMID: 36284411, FI: 4.0

Sanchez-Campillo M, Pastor-Fajardo MT, Sabater-Molina M, ..., Larque E. Critical Steps for Human Gut Exfoliome RNA Profiling Analysis Using Non-Invasive Stool Samples. Annals of Nutrition and Metabolism, 2022, 78, 80-90, PMID: 34788767, FI: 3.9

Codina P, Domingo M, Barcelo E, ..., Pascual-Figal DA* et al. Sacubitril/valsartan affects pulmonary arterial pressure in heart failure with preserved ejection fraction and pulmonary hypertension. Esc Heart Failure, 2022, 9, 2170-2180, PMID: 35588235, FI: 3.8

Gimeno JR*, Olivotto I, Rodriguez AI et al. Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry. Esc Heart Failure, 2022, 9, 2189-2198, PMID: 36255281, FI: 3.8

Martinez-Campelo L, Cruz R, Blanco-Verea A, ..., Sabater-Molina M et al. Searching for genetic modulators of the phenotypic heterogeneity in Brugada syndrome. Plos one, 2022, 17, e0263469, PMID: 35231055, FI: 3.7

Sabater Molina M*, Nicolas Rocamora E, Bendicho AI, ..., Gimeno Blanes JR*. Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease. Plos one, 2022, 17, e0263140, PMID: 35120165, FI: 3.7

Guler MN, Tscheiller NM, Sabater-Molina M et al. Evidence for reciprocal network interactions between injured hearts and cancer. Frontiers in Cardiovascular Medicine, 2022, 9, 929259, PMID: 35911555, FI: 3.6

Garcia-Serna AM*, Morales E*, Cantero-Cano E, ..., Martin-Orozco E*. Cytokine production by newborns: influence of sex and season of birth. Pediatric Research, 2022, 10.1038/s41390-022-02153-1 [doi], PMID: 35945266, FI: 3.6

Caravaca Perez P, Gonzalez-Juanatey JR, Nuche J, ..., Pascual Figal D* et al. Renal Function Impact in the Prognostic Value of Galectin-3 in Acute Heart Failure. Frontiers in Cardiovascular Medicine, 2022, 9, 861651, PMID: 35463785, FI: 3.6

Esteve-Pastor MA*, Ruiz-Ortiz M, Muniz J, ..., Marin F*. Impact of Integrated Care Management on Clinical Outcomes in Atrial Fibrillation Patients: A Report From the FANTASIIA Registry. Frontiers in Cardiovascular Medicine, 2022, 9, 856222, PMID: 35586656, FI: 3.6

Cruz R, Diz-de Almeida S, Lopez de Heredia M, ..., Barreda-Sanchez M et al. Novel genes and sex differences in COVID-19 severity. Human Molecular Genetics, 2022, 31, 3789-3806, PMID: 35708486, FI: 3.5

Fischlein T, Caporali E, Folliguet T, ..., Garcia-Puente J et al. Randomized controlled trial between conventional versus sutureless bioprostheses for aortic valve replacement: Impact of mini and full sternotomy access at 1-year follow-up. International Journal of Cardiology, 2022, S0167-5273(22)01179-2 [pii], PMID: 35944771, FI: 3.5

Gonzalez-Del-Hoyo M, Rodriguez-Leor O, Cid-Alvarez AB, ..., Lopez-Palop R et al. Short-term mortality differs between men and women according to the presence of previous cardiovascular disease: Insights from a nationwide STEMI cohort. International Journal of Cardiology, 2022, 367, 90-98, PMID: 36030132, FI: 3.5

Anguita Sanchez M, Marin F, Masjuan J et al. Impact of heart failure on the clinical profile and outcomes in patients with atrial fibrillation treated with rivaroxaban. Data from the EMIR study. , 2022, 10.5603/CJ.a2022.0091 [doi], PMID: 36200548, FI: 3.487

Ding WY, Rivera-Caravaca JM*, Marin F et al. Number needed to treat for net effect of anticoagulation in atrial fibrillation: Real-world vs. clinical-trial evidence. British Journal of Clinical Pharmacology, 2022, 88, 282-289, PMID: 34192808, FI: 3.4

Esteve-Pastor MA*, Rivera-Caravaca JM, Ruiz-Ortiz M, ..., Marin F*. A comparison of front-line oral anticoagulants for the treatment of non-valvular atrial fibrillation: effectiveness and safety of direct oral anticoagulants in the FANTASIIA registry. Expert Opinion on Pharmacotherapy, 2022, 23, 1457-1465, PMID: 35924672, FI: 3.2

Valverde-Bolivar E, Simonelli-Munoz AJ, Rivera-Caravaca JM et al. Occupational Therapy in Severe Mental Disorder-A Self-Controlled Quasi-Experimental Study. , 2022, 10, PMID: 35326971, FI: 3.16

Arribas-Leal JM, Rivera-Caravaca JM, Hernandez-Torres A, ..., Herrero-Martinez JA. Incidence and predictors of sternal surgical wound infection in cardiac surgery: A prospective study. International Wound Journal, 2022, 10.1111/iwj.13938 [doi], PMID: 36168924, FI: 3.1

Martinez-Villar M, Tello-Montoliu A*, Olea A, ..., Garcia Navarro M*, ..., Pascual D*. Global longitudinal strain assessment of cardiac function and extravascular lung water formation after diving using semi-closed circuit rebreather. European Journal of Applied Physiology, 2022, 122, 945-954, PMID: 35059801, FI: 3.0

Sanmartin Fernandez M, Anguita Sanchez M, Arribas F, ..., Marin F. Outcomes and predictive value of the 2MACE score in patients with atrial fibrillation treated with rivaroxaban in a prospective, multicenter observational study: The EMIR study. Cardiology Journal, 2022, 29, 601-609, PMID: 35621092, FI: 2.9

Antonogeorgos G, Panagiotakos DB, Priftis KN, ..., Garcia-Marcos L et al. Parental Education Moderates the Relation between Physical Activity, Dietary Patterns and Atopic Diseases in Adolescents. , 2022, 9, PMID: 35626863, FI: 2.835

Morales E, Alcantara-Lopez MV, Cabezas-Herrera J, ..., Garcia-Marcos L. The Nutrition in Early Life and Asthma (NELA) birth cohort study: Rationale, design, and methods. Paediatric and Perinatal Epidemiology, 2022, 36, 310-324, PMID: 34841558, FI: 2.8

Rivera-Caravaca JM, Nunez-Gil IJ, Lip GYH, ..., Marin F*. Chronic Oral Anticoagulation Therapy and Prognosis of Patients Admitted to Hospital for COVID-19: Insights from the HOPE COVID-19 Registry. International Journal of Clinical Practice, 2022, 2022, 7325060, PMID: 35685504, FI: 2.6

de la Torre Hernandez JM, Palop RL, Jimenez Mazuecos JM, ..., Pinar E* et al. Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents: EPIC05-Sierra75 study. Journal of Geriatric Cardiology, 2022, 19, 354-366, PMID: 35722037, FI: 2.5

Garcia-Garcia A, Alvarez-Sala-Walther LA, Lee HY, ..., Pascual-Figal D*, Camafort M. Is there sufficient evidence to justify changes in dietary habits in heart failure patients? A systematic review. Korean Journal of Internal Medicine, 2022, 37, 37-47, PMID: 34482681, FI: 2.4

Wiebe J, Hofmann FJ, West N et al. COLABORADORES: ..., Pinar E et al. Outcomes of 10,312 patients treated with everolimus-eluting bioresorbable scaffolds during daily clinical practice - results from the European Absorb Consortium. Catheterization and Cardiovascular Interventions, 2022, 99, 533-540, PMID: 34463427, FI: 2.3

Iqtadar S, Khan A, Mumtaz SU, Pascual-Figal DA* et al. Tocilizumab therapy for severely-ill COVID-19 pneumonia patients: a single-centre retrospective study. Journal of Physiology and Pharmacology, 2022, 73, PMID: 36696245, FI: 2.2

Haroon MZ, Farooq U, Ashraf S, ..., Pascual-Figal DA* et al. Colchicine anti-inflammatory therapy for non-intensive care unit hospitalized COVID-19 patients: results from a pilot open-label, randomized controlled clinical trial. Journal of Physiology and Pharmacology, 2022, 73, PMID: 36302537, FI: 2.2

Marin F, Fernandez MS, Lekuona I et al. Rivaroxaban for the prevention of outcomes in patients with atrial fibrillation in clinical practice: an indirect comparison of national and international registries. Journal of Comparative Effectiveness Research, 2022, 11, 1173-1184, PMID: 36148923, FI: 2.1

Laufer G, Strauch JT, Terp KA, ..., Arribas JM et al. Real-world 6-month outcomes of minimally invasive aortic valve replacement with the EDWARDS INTUITY Elite valve system. , 2022, ivac083 [pii], PMID: 35394527, FI: 1.978

Miralles-Lopez JC, Andujar-Espinosa R, Bravo-Gutierrez FJ, ..., Perez-Fernandez V. Analysis of response of severe eosinophilic asthmatic patients to benralizumab. Allergologia et Immunopathologia, 2022, 50, 163-168, PMID: 36335460, FI: 1.8

Antonogeorgos G, Mandrapylia M, Liakou E, ..., Garcia-Marcos L et al. Hierarchical analysis of Mediterranean Dietary pattern on atopic diseases' prevalence in adolescence: The Greek Global Asthma Network study. Allergologia et Immunopathologia, 2022, 50, 114-120, PMID: 36086971, FI: 1.8

Aranda-Domene R*, Minano-Frutos C, Arribas-Leal JM, ..., Canovas S*. Accessory left atrial cords: A case report and literature review. Journal of Cardiac Surgery, 2022, 10.1111/jocs.16608 [doi], PMID: 35578332, FI: 1.6

Jurado-Roman A, Minana G, Salinas P, ..., Lacunza J* et al. Overlapping versus single long stents in long chronic total occlusions: insights of the Iberian CTO Registry. Minerva Cardiology and Angiology, 2022, 10.23736/S2724-5683.22.06046-X [doi], PMID: 35420282, FI: 1.6

AYUDAS CONCEDIDAS EN 2022

TOTAL DE AYUDAS CONCEDIDAS

Nº Ayudas

3.39M €

Financiación

TOTAL DE AYUDAS RECURSOS HUMANOS CONCEDIDAS

Nº Ayudas

0.21M €

Financiación

TOTAL DE AYUDAS PROYECTOS I+D+i CONCEDIDAS

Nº Ayudas Europeas

0.0M €

Financiación Europea

Nº Ayudas Nacionales

3.13M €

Financiación Nacional

Nº Ayudas Regionales

0.05M €

Financiación Regional

TOTAL DE REDES CONCEDIDAS

Nº Ayudas

0.0M €

Financiación

OTRAS AYUDAS COMPETITIVAS CONCEDIDAS (MOVILIDAD, ORGANIZACIÓN DE EVENTOS CIENTÍFICOS, ...)

Nº Ayudas

0.0K €

Financiación

PROYECTOS DE I+D+i Y AYUDAS DE RRHH ACTIVAS EN 2022

TOTAL AYUDAS

RECURSOS HUMANOS

REDES

PROYECTOS INTERNACIONALES

PROYECTOS NACIONALES

PROYECTOS REGIONALES

INICIADA EN 2022

Nº Estudios

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

ACTIVOS EN 2022

100

Nº Estudios

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

FACTURACIÓN EN 2022

0.38M €

Facturado

Nº Tesis (1 con mención internacional)